張文祥 副研究員－論文

PUBLICATIONS

 (*denotes the corresponding author):

  1. Chou RH, Wen HC, Liang WG, Lin SC, Yuan HW, Wu CW, Chang WSW*. (2011) Suppression of the invasion and migration of cancer cells by SERPINB family genes and their derived peptides. Oncol. Rep. (in press)
  2. Chou RH, Lin SC, Wen HC, Wu CW, Chang WSW* (2011) Epigenetic activation of human kallikrein 13 enhances malignancy of lung adenocarcinoma by promoting N-cadherin expression and laminin degradation. Biochem. Biophys. Res. Commun. 409:442-447.
  3. Chen YW, Chou HC, Lyu PC, Yin HS, Huang FL, Chang WSW, Fan CY, Tu IF, Lai TC, Lin ST, Lu YC, Wu CL, Huang SH, Chan HL. (2011) Mitochondrial proteomics analysis of tumorigenic and metastatic breast cancer markers. Funct. Integr. Genomics 11:225-239.
  4. Chen JC, Uang BJ, Lyu PC, Chang JY, Liu KJ, Kuo CC, Hsieh HP, Wang HC, Cheng CS, Ch.ang YH, Chang MDT, Chang WSW*, Lin CC. (2010) Design and synthesis of α-ketoamides as Cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis. J. Med. Chem. 53:4545–4549.
  5. Wu CC, Liu MT, Chang YT, Fang CY, Chou SP, Liao HW, Kuo KL, Hsu SL, Chen YR, Wang PW, Chen YL, Chuang HY, Lee CH, Chen M, Chang WSW, Chen JY. (2010) Epstein-Barr Virus DNase (BGLF5) induces genomic instability in human epithelial cells. Nucleic Acids Res. 38:1932-1949.
  6. Chen YK, Chang WSW, Wu IC, Li LH, Yang SF, Chen JY, Hsu MC, Chen SH, Wu DC, Lee JM, Huang CH, Goan YG, Chou SH, Huang CT, Wu MT. (2010) Molecular characterization of invasive subpopulations from an esophageal squamous cell carcinoma cell line. Anticancer Res. 30:727-736.
  7. Huang CC, Chang WSW*. (2009) Cooperation between NRF2 and YY1 transcription factors is essential for triggering the transcription of the PREPL-C2ORF34 bidirectional gene pair. BMC Mol. Biol. 10:67.
  8. Chen T, Lee TR, Liang WG, Chang WSW*, Lyu PC. (2009) Identification of trypsin-inhibitory site and structure determination of human SPINK2 serine proteinase inhibitor. Proteins 77:209-219.
  9. De Koning PJA, Bovenschen N, Leusink FKJ, Broekhuizen R, Quadir R, van Gemert JTM, Hordijk GJ, Chang WSW, van der Tweel I, Tilanus MGJ, Kummer JA (2009) Down-regulation of SERPINB13 expression in head and neck squamous cell carcinomas associates with poor clinical outcome. Int. J. Cancer 125:1542-1550.
  10. Chen PY, Chang WSW*, Lai YK, Wu CW. (2009) c-Myc regulates the coordinated transcription of brain disease-related PDCD10-SERPINI1 bidirectional gene pair. Mol. Cell. Neurosci. 42:23-32.
  11. Chang YP, Mahadeva R, Chang WSW, Chu YH. (2009) Small-molecule peptides inhibit Z α1-antitrypsin polymerization. J. Cell. Mol. Med.13: 2304-2316.
  12. Tsai T, Ji HT, Chiang PC, Chou RH, Chang WSW, Chen CT (2009) ALA-PDT results in phenotypic changes and decreased cellular invasion in surviving cancer cells. Laser Surg. Med. 41:305-315.
  13. Lin KM, Hsu CH, Chang WSW, Chen CT, Lee TW, Chen CT (2008) Human Breast Tumor Cells Express Multimodal Imaging Reporter Genes. Mol. Imaging Biol. 10:253-263.
  14. Chang WSW*, Chou RH, Wu CW, Chang JY. (2007) Human tissue kallikreins as prognostic biomarkers and as potential targets for anticancer therapy. Expert Opin. Ther. Pat. 17:1227-1240.
  15. Chen PY, Chang WSW*, Chou RH, Lai YK, Lin SC, Chi CY, Wu CW. (2007) Two non-homologous brain diseases-related genes, SERPINI1 and PDCD10, are tightly linked by an asymmetric bidirectional promoter in an evolutionarily conserved manner. BMC Mol. Biol. 8:2.
  16. Chang WSW*, Wu HR, Yeh CT, Wu CW, Chang JY. (2007) Lysosomal cysteine proteinase cathepsin S as a potential target for anti-cancer therapy. J. Cancer Mol. 3:5-14.
  17. Sher YP, Chou CC, Chou RH, Wu HM, Chang WSW, Chen CH, Yang PC, Wu CW, Yu CL, Peck K. (2006) Human kallikrein 8 Suppresses cancer cell invasiveness to yield favorable clinical outcome in non-small cell lung cancer. Cancer Res. 66:11763-11770.
  18. Chang YP, Mahadeva R, Chang WSW, Shukla A, Dafforn TR, Chu YH. (2006) Identification of a 4-mer peptide inhibitor that effectively blocks the polymerization of pathogenic Z 1-antitrypsin. Am. J. Resp. Cell Mol. Biol. 35:540-548.
  19. Chang YP, Chang WSW, Chu YH. (2005) Alpha1-antitrypsin deficiency and conformational diseases. Chemistry 63:419-430.
  20. Chou RH, Lin KC, Lin SC, Cheng JY, Wu CW, Chang WSW*. (2004) Cost-effective trapezoidal modified Boyden chamber with comparable accuracy to a commercial apparatus. BioTechniques 37:724-726.
  21. Chen JS, Chen A, Chang LC, Chang WSW, Lee HS, Lin SH, Lin YF. (2004) Mouse model of membranous nephropathy induced by cationic bovine serum albumin: antigen does-response relations and strain differences. Nephrol. Dial. Transpl. 19:2721-2728.
  22. Huang SP, Wu WJ, Chang WSW, Wu MT, Chen YY, Chen YJ, Yu CC, Wu TT, Lee YH, Huang JK, Huang CH. (2004) P53 codon 72 and P21 codon 31 polymorphisms in prostate cancer. Cancer Epidem. Biomar. 13:2217-2224.
  23. Huang SP, Chou YH, Chang WSW, Wu MT, Chen YY, Yu CC, Wu TT, Lee YH, Huang JK, Wu WJ, Huang CH. (2004) Association between vitamin D receptor polymorphisms and prostate cancer risk in a Taiwanese population. Cancer Lett. 207:69-77.
  24. Chang WSW*, Lin SC, Lin KC, Kao YR, Chou RH, Chi CY, Wu CW. (2003) The retrospect and prospect of in vitro tumor invasion assay technique. Instrum. Today 134:42-50.
  25. Huang SP, Chou YH, Chang WSW, Wu MT, Yu CC, Wu TT, Lee YH, Huang JK, Wu WJ, Huang CH. (2003) Androgen receptor gene polymorphism and prostate cancer in Taiwan. J. Formos. Med. Assoc. 102:680-686.
  26. Chang WSW, Chang NT, Lin SC, Wu CW, Wu FYH. (2000) Tissue-specific cancer-related serpin gene cluster at human chromosome band 3q26. Gene. Chromosome Canc. 27:240-255.
  27. Gooptu B, Hazes B, Chang WSW, Dafforn TR, Carrell RW, Read RJ, Lomas DA. (2000) Inactive conformation of the serpin 1-antichymotrypsin indicates two stage insertion of the reactive loop: implications for inhibitory function and conformational disease. Proc. Natl. Acad. Sci. U.S.A. 97:67-72.
  28. Chang TC, Lin KC, Chiang CC, Yang YP, Chang WSW. (2000) Satellite Hole Spectroscopy of Thrombin-Aptamer Complexes. ChemBioChem 3:197-200.
  29. Mahadeva R, Chang WSW, Dafforn TR, Oakley DJ, Foreman RC, Calvin J, Wight DG, Lomas DA. (1999) Heteropolymerization of S, I, and Z 1-antitrypsin and liver cirrhosis. J. Clin. Invest. 103:999-1006.
  30. Liao WC, Chang WSW, Wu FY. (1999) Re: Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies. J. Natl. Cancer Inst. 91:285-286.
  31. Chang WSW, Lomas DA. (1998) Latent 1-antichymotrypsin: a molecular explanation for the inactivation of 1-antichymotrypsin in chronic bronchitis and emphysema. J. Biol. Chem. 273:3695-3701.
  32. Skinner R, Chang WSW, Huntingdon JA, Jin L, Abrahams JP, Carrell RW and Lomas DA. (1998) Implications for function and therapy of a 2.9 Å structure of binary-complexed antithrombin. J. Mol. Biol. 283:9-14. (The first 2 authors contributed equally to this work)
  33. Chang WSW*, Harper PL. (1997) Commercial antithrombin concentrate contains inactive L-forms of antithrombin. Thromb. Haemostasis. 77:323-328.
  34. Chang WSW*, Whisstock J, Hopkins PCR, Lesk AM, Carrell RW and Wardell MR. (1997) Importance of the release of strand 1C to the polymerization mechanism of inhibitory serpins. Protein Sci. 6:89-98.
  35. Bottomley SP, Chang WSW. (1997) The effects of reactive center loop length upon serpin polymerisation. Biochem. Bioph. Res. Commun. 241: 264-269.
  36. Fitton HL, Pike RN, Carrell RW, Chang WSW*. (1997) Mechanisms of antithrombin polymerisation and heparin activation probed by the insertion of synthetic reactive loop peptides. Biol. Chem. 378:1059-1063.
  37. Wardell MR, Chang WSW, Bruce D, Skinner R, Lesk AM, Carrell RW. (1997) Preparative induction and characterization of L-antithrombin: a structural homologue of latent plasminogen activator inhibitor-1. Biochemistry 36:13133-13142.
  38. Hopkins PCR, Chang WSW, Wardell MR, Stone SR. (1997) Inhibitory mechanism of serpins: mobility of the C-terminal region of the reactive-site loop. J. Biol. Chem. 272:3905-3909.
  39. Chang WSW*, Wardell MR, Lomas DA and Carrell RW. (1996) Probing serpin reactive-loop conformations by proteolytic cleavage. Biochem. J. 314:647-653.
  40. Lomas DA, Elliott PR, Chang WSW, Wardell MR and Carrell RW. (1995) Preparation and characterisation of latent 1-antitrypsin. J. Biol. Chem. 270:5282-5288.
  41. Lomas DA, Evans DL, Stone SR, Chang WSW, Carrell RW. (1993) Effect of the Z mutation on the physical and inhibitory properties of 1-antitrypsin. Biochemistry 32:500-508.
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