張光裕 副研究員級主治醫師－論文

PUBLICATIONS

1. Chia-Hung Chien, Jian-Ying Chuang, Shun-Tai Yang, Wen-Bin Yang, Pin-Yuan Chen, Tsung-I Hsu, Chih-Yuan Huang, Wei-Lun Lo, Ka-Yen Yang, Ming-Sheng Liu, Jui-Mei Chu, Pei-Hsuan Chung, Jr-Jiun Liu, Shao-Wen Chou, Shang-Hung Chen, Kwang-Yu Chang*. Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets. J Biomed Sci 2019 Oct 19;26(1):77.
2. Chia-Jui Yen*, Hsiao-Hui Tsou, Ching-Yun Hsieh, Chang-Yao Chu, Chang-Fang Chiu, Chih-Cheng Chen, Chao-Jung Tsao, Kuo-Yang Tsai, Sen-Tien Tsai, Jang-Yang Chang, Kwang-Yu Chang*. Sequential therapy of neoadjuvant biochemotherapy with cetuximab, paclitaxel, and cisplatin followed by cetuximab-based concurrent bioradiotherapy in high-risk locally advanced oral squamous cell carcinoma: final analysis of a phase 2 clinical trial. Head Neck 2019 Jun;41(6):1703-12.
3. Kwang-Yu Chang, Chih-Ta Huang, Tsung-I Hsu, Che-Chia Hsu, Jr-Jiun Liu, Cheng-Keng Chuang, Jan-Jong Hung, Wen-Chang Chang, Kelvin K. Tsai, Jian-Ying Chuang*. Stress stimuli induce cancer-stemness gene expression via Sp1 activation leading to therapeutic resistance in glioblastoma. Biochem Biophys Res Commun. 2017 Nov 4;493(1):14-19.
4. Kwang-Yu Chang, Tsung-I Hsu, Che-Chia Hsu, Shan-Yin Tsai, Jr-Jiun Liu, Shao-Wen Chou, Ming-Sheng Liu, Jing-Ping Liou, Chiung-Yuan Ko, Kai-Yun Chen, Jan-Jong Hung, Wen-Chang Chang, Cheng-Keng Chuang, Tzu-Jen Kao*, Jian-Ying Chuang*. Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O6-methylguanine-DNA methyltransferase. Redox Biol. 2017 Oct;13:655-664.
5. Jinn-Yuan Hsu, Jang-Yang Chang, Kwang-Yu Chang, Wen-Chang Chang, Ben-Kuen Chen. Epidermal growth factor-induced pyruvate dehydrogenase kinase 1 expression enhances head and neck squamous cell carcinoma metastasis via up-regulation of fibronectin. FASEB J. 2017 Oct;31(10):4265-4276.
6. Che-Chia Hsu, Wen-Chang Chang, Tsung-I Hsu, Jr-Jiun Liu, Shiu-Hwa Yeh, Jia-Yi Wang, Jing-Ping Liou, Chiung-Yuan Ko, Kwang-Yu Chang*, Jian-Ying Chuang*. Suberoylanilide hydroxamic acid represses glioma stem-like cells. J Biomed Sci. 2016 Nov 18;23(1):81.
7. Huang-Yu Yang, Joseph Barbi, Chao-Yi Wu, Ying Zheng, Paolo D.A. Vignali, Xingmei Wu, Jin-Hui Tao, Benjamin V. Park, Shashika Bandara, Lewis Novack, Xuhao Ni, Xiaoping Yang, Kwang-Yu Chang, Ren-Chin Wu, Junran Zhang, Chih-Wei Yang, Drew M. Pardoll, Huabin Li, Fan Pan. MicroRNA-17 Modulates Regulatory T Cell Function by Targeting Co-regulators of the Foxp3 Transcription Factor. Immunity. 2016 Jul 19;45(1):83-93.
8. Shang Hung Chen, Ching Chuan Kuo, Chien Feng Li, Chun Hei Antonio Cheung, Tsui Chun Tsou, Huai Chih Chiang, Yun Ning Yang, Shin Lun Chang, Li Ching Lin, Hsin Yi Pan, Kwang-Yu Chang, Jang Yang Chang. O6 -methylguanine DNA methyltransferase repairs platinum-DNA adducts following cisplatin treatment and predicts prognoses of nasopharyngeal carcinoma. Int J Cancer. 2015 Sep 15;137(6):1291-305.
9. Chi-Ruei Huang, Chung-Ta Lee, Kwang-Yu Chang, Wen-Chang Chang, Yao-Wen Liu, Jenq-Chang Lee, Ben-Kuen Chen. Down-regulation of ARNT promotes cancer metastasis by activating the fibronectin/integrin β1/FAK axis. Oncotarget. 2015 May 10;6(13):11530-46.
10. Jinn-Yuan Hsu, Kwang-Yu Chang, Shang-Hung Chen, Chung-Ta Lee, Sheng-Tsung Chang, Hung-Chi Cheng, Wen-Chang Chang, Ben-Kuen Chen. Epidermal growth factor-induced cyclooxygenase-2 enhances head and neck squamous cell carcinoma metastasis through fibronectin up-regulation. Oncotarget. 2015 Jan 30;6(3):1723-39.
11. Sen-Tien Tsai, Tung-Yiu Wong, Chun-Yen Ou, Sheen-Yie Fang, Ken-Chung Chen, Jenn-Ren Hsiao, Cheng-Chih Huang, Wei-Ting Lee, Hung-I Lo, Jehn-Shyun Huang, Jiunn-Liang Wu, Chia-Jui Yen, Wei-Ting Hsueh, Yuan-Hua Wu, Ming-Wei Yang, Forn-Chia Lin, Jang-Yang Chang, Kwang-Yu Chang, Shang-Yin Wu, Hsiao-Chen Liao, Chen-Lin Lin, Yi-Hui Wang, Ya-Ling Weng, Han-Chien Yang, Jeffrey S. Chang. The interplay between alcohol consumption, oral hygiene, ALDH2 and ADH1B in the risk of head and neck cancer. Int J Cancer. 2014 Nov 15;135(10):2424-36.
12. Shang-Yin Wu, Yuan-Hua Wu, Ming-Wei Yang, Wei-Ting Hsueh, Jenn-Ren Hsiao, Sen-Tien Tsai, Kwang-Yu Chang, Jeffrey S Chang, Chia-Jui Yen. Comparison of concurrent chemoradiotherapy versus neoadjuvant chemotherapy followed by radiation in patients with advanced nasopharyngeal carcinoma in endemic area: experience of 128 consecutive cases with 5 year follow-up. BMC Cancer. 2014 Oct 28;14:787.
13. Ying-En Lee, Hong-Lin He, Sung-Wei Lee, Tzu-Ju Chen, Kwang-Yu Chang, Chung-Hsi Hsing, Chien-Feng Li. AMACR overexpression as a poor prognostic factor in patients with nasopharyngeal carcinoma. Tumour Biol. 2014 Aug;35(8):7983-91.
14. Tzu-Ju Chen, Sung-Wei Lee, Li-Ching Lin, Ching-Yih Lin, Kwang-Yu Chang, Chien-Feng Li. Cyclin-dependent kinase 4 overexpression is mostly independent of gene amplification and constitutes an independent prognosticator for nasopharyngeal carcinoma. Tumour Biol. 2014 Jul;35(7):7209-16.
15. Cheng-Chih Huang, Wei-Ting Lee, Sen-Tien Tsai, Chun-Yen Ou, Hung-I Lo, Tung-Yiu Wong, Sheen-Yie Fang, Ken-Chung Chen, Jehn-Shyun Huang, Jiunn-Liang Wu, Chia-Jui Yen, Wei-Ting Hsueh, Yuan-Hua Wu, Ming-Wei Yang, Forn-Chia Lin, Jang-Yang Chang, Kwang-Yu Chang, Shang-Yin Wu, Jenn-Ren Hsiao, Chen-Lin Lin, Yi-Hui Wang, Ya-Ling Weng, Han-Chien Yang, Jeffrey S. Chang. Tea consumption and risk of head and neck cancer. PLoS One. 2014 May 5;9(5):e96507.
16. Han-Ping Hsu, Chien-Feng Li, Sung-Wei Lee, Wen-Ren Wu, Tzu-Ju Chen, Kwang-Yu Chang, Shih-Shin Liang, Chia-Jung Tsai, Yow-Ling Shiue. Overexpression of stathmin 1 confers an independent prognostic indicator in nasopharyngeal carcinoma. Tumour Biol. 2014 Mar;35(3):2619-29.
17. Li-Jung Ma, Sung-Wei Lee, Li-Ching Lin, Tzu-Ju Chen, I-Wei Chang, Han-Ping Hsu, Kwang-Yu Chang, Hsuan-Ying Huang, Chien-Feng Li. Fibronectin overexpression is associated with latent membrane protein 1 expression and has independent prognostic value for nasopharyngeal carcinoma. Tumour Biol. 2014 Feb;35(2):1703-12.
18. Jeffrey S. Chang, Hung-I Lo, Tung-Yiu Wong, Cheng-Chih Huang, Wei-Ting Lee, Sen-Tien Tsai, Ken-Chung Chen, Chia-Jui Yen, Yuan-Hua Wu, Wei-Ting Hsueh, Ming-Wei Yang, Shang-Yin Wu, Kwang-Yu Chang, Jang-Yang Chang, Chun-Yen Ou, Yi-Hui Wang, Ya-Ling Weng, Han-Chien Yang, Fang-Ting Wang, Chen-Lin Lin, Jehn-Shyun Huang, Jenn-Ren Hsiao. Investigating the association between oral hygiene and head and neck cancer. Oral Oncol 2013 Oct;49(10):1010-7.
19. Kun-Ming Chung, Sheng-Tsung Chang, Wen-Tsung Huang, Chin-Li Lu, Hung-Chang Wu, Wei-Shou Hwang, Kwang-Yu Chang, Shih-Sung Chuang. Bcl-6 expression and lactate dehydrogenase level predict prognosis of primary gastric diffuse large B-cell lymphoma. J Formos Med Assoc 2013 Jul;112(7):382-9.
20. Kwang-Yu Chang, Shan-Yin Tsai, Shang-Hung Chen, Hsiao-Hui Tsou, Chia-Jui Yen, Ko-Jiunn Liu, Hsun-Lang Fang, Hung-Chang Wu, Bin-Fay Chuang, Shao-Wen Chou, Careen K. Tang, Shyun-Yeu Liu, Pei-Jung Lu, Ching-Yu Yen, Jang-Yang Chang. Dissecting the EGFR-PI3K-AKT pathway in oral cancer highlights the role of the EGFR variant III and its clinical relevance. J Biomed Sci. 2013 Jun;20:43.
21. Ming-Yuan Hong, Chin-Chung Tseng, Chia-Chang Chuang, Chia-Ling Chen, Yu-Huei Lin, Chia-Yuan Hsieh, Yu-Tzu Chang, Chung-Hsi Hsing, Kwang-Yu Chang, Chiou-Feng Lin. Uropathogenic Escherichia coli causes cortical tubular necrotic cell death and the release of macrophage migration inhibitory factor. Cytokine. 2013 Mar;61(3):945-52.
22. Jenn-Ren Hsiao, Chun-Yen Ou, Hung-I Lo, Cheng-Chih Huang, Wei-Ting Lee, Jehn-Shyun Huang, Ken-Chung Chen, Tung-Yiu Wong, Sen-Tien Tsai, Chia-Jui Yen, Yuan-Hua Wu, Wei-Ting Hsueh, Ming-Wei Yang, Shang-Yin Wu, Jang-Yang Chang, Kwang-Yu Chang, Chen-Lin Lin, Fang-Ting Wang, Yi-Hui Wang, Ya-Ling Weng, Han-Chien Yang, Jeffrey S. Chang. Allergies and risk of head and neck cancer: an original study plus meta-analysis. PLoS One. 2013;8(2):e55138.
23. Chia-Jui Yen, Yih-Jyh Lin, Chia-Sheng Yen, Hung-Wen Tsai, Ting-Fen Tsai, Kwang-Yu Chang Wei-Chien Huang, Pin-Wen Lin, Chi-Wu Chiang, Ting-Tsung Chang. Hepatitis B Virus X protein upregulates mTOR signaling through IKKβ to increase cell proliferation and VEGF production in hepatocellular carcinoma. PLoS One. 2012;7(7):e41931.
24. Chia-Chi Chien, Ivan M. Kempson, Cheng Liang Wang, H.H. Chen, Yeukuang Hwu, N.Y. Chen, T.K. Lee, Cyril Petibois, Kelvin K.-C. Tsai, Ming-Sheng Liu, Kwang-Yu Chang, C.S. Yang, G. Margaritondo. Complete microscale profiling of tumor microangiogenesis A microradiological methodology reveals fundamental aspects of tumor angiogenesis and yields an array of quantitative parameters for its characterization. Biotechnol Adv. 2013 May-Jun;31(3):396-401.
25. Kwang-Yu Chang, Shan-Yin Tsai, Ching-Ming Wu, Chia-Jui Yen, Bin-Fay Chuang, Jang-Yang Chang. Novel PI3K/mTOR dual inhibitor, NVP-BGT226, displays potent growth-inhibitory activity against human head and neck cancer cells in vitro and in vivo. Clin Cancer Res. 2011 Nov 15;17(22):7116-26.
26. Yun-Ju Chen, Wei-Chien Huang, Ya-Ling Wei, Sheng-Chieh Hsu, Ping Yuan, Heather Y. Lin, Ignacio I. Wistuba, J. Jack Lee, Chia-Jui Yen, Wu-Chou Su, Kwang-Yu Chang, Wen-Chang Chang, Tse-Chuan Chou, Chao-Kai Chou, Chang-Hai Tsai, Mien-Chie Hung. Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells. PLoS One. 2011;6(6):e21428.
27. Chun Hei Antonio Cheung, LiTing Cheng, Kwang-Yu Chang, Huang-Hui Chen, Jang-Yang Chang. Investigations of survivin: the past, present and future. Front Biosci. 2011 Jan 1;16:952-61.
28. Shang-Wen Chen, Sheng-Tsung Chang, Chin-Li Lu, Wei-Shou Hwang, Chao-Jung Tsao, Wen-Tsung Huang, Kwang-Yu Chang, Shih-Sung Chuang. Upper aerodigestive tract lymphoma in Taiwan. J Clin Pathol. 2010 Oct;63(10):888-93.
29. Wan-Chen Huang, Shu-Ting Chen, Wei-Chiao Chang, Kwang-Yu Chang, Wen-Chang Chang and Ben-Kuen Chen. Involvement of aryl hydrocarbon receptor nuclear translocator in EGF-induced c-Jun/Sp1-mediated gene expression. Cell Mol Life Sci. 2010 Oct;67(20):3523-33.
30. Kwang-Yu Chang, Jang-Yang Chang, Yun Yen. Increasing incidence of intrahepatic cholangiocarcinoma and its relationship to chronic viral hepatitis. J Natl Compr Canc Netw 2009 Apr;7(4):423-7.
31. Kwang-Yu Chang, Meng-Ru Shen, Mei-Yi Lee, Wen-Lin Wang, Wu-Chou Su, Wen-Chang Chang , Ben-Kuen Chen. Epidermal growth factor-activated ARNT/HIF-1β signal pathway up-regulates cyclooxygenase-2 gene expression associated with squamous cell carcinoma. J Biol Chem 2009 Apr; 284(15): 9908-16.
32. Kwang-Yu Chang, Jang-Yang Chang, Joseph Chao, Yun Yen. Modern staging and utility of PET imaging in esophageal cancer management. J Natl Compr Canc Netw 2008 Oct; 6(9): 862-869.
33. S-S Chuang, H Ye , S-F Yang, W-T Huang , H-K Chen, P-P Hsieh, W-S Hwang, Kwang-Yu Chang, C-L Lu, M-Q Du. Perforation predicts poor prognosis in patients with primary intestinal diffuse large B-cell lymphoma. Histopathology 2008 Oct; 53(4): 432-440.
34. Jen-Hui Tsou, Kwang-Yu Chang, Wei-Chiao Wang, Joseph T. Tseng, Wu-Chou Su, Liang-Yi Hung, Wen-Chang Chang, Ben-Kuen Chen. Nucleolin regulates c-Jun/Sp1-dependent transcriptional activation of cPLA2alpha in phorbol ester-treated non-small cell lung cancer A549 cells. Nucleic Acids Res 2008 Jan ;36(1):217-227.